The Getty Center in Brentwood. (Gary Friedman / Los Angeles Times / July 26, 2012)

Carmageddon will return in late September when a portion of the 405 Freeway will be shut down for 53 hours. As a result, the Getty Center will close its doors to the public and most staff on Sept. 29 and 30, which are a Saturday and Sunday. It will reopen to the public on Oct. 2.

The Getty Villa in Pacific Palisades won't be affected by the closures, the museum said. During the first Carmageddon in 2011, the Getty Center also closed to the public for two days.

The second installment of the freeway project involves the widening of the 405 and includes demolition work on the Mulholland Drive bridge. The 405 Freeway will be shut down between the 10 and 101 freeways while the work is done.

The Getty said that a performance by the Calder Quartet that was scheduled for Sept. 29 has been rescheduled for Oct. 5.